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Product Details
Nrf2 is a three-ingredient formula designed to support antioxidant defences. Cruciferous vegetables of the brassica family, such as broccoli, have long been recognized for their ability to support antioxidant activity, thereby maintaining healthy cells and tissues. They provide a source of the bioactive constituent sulforaphane, one of the most powerful activators of phase II enzyme function in the liver, protecting tissues from oxidative stress and reactive substances. Sulforaphane and resveratrol promote the activity of nuclear factor erythroid 2-related factor 2 (Nrf2), a transcription factor that supports robust, long-lasting expression of numerous genes responsible for protection against oxidative stress. Nrf2 also supports the biosynthesis of glutathione, a vital component of cellular antioxidant systems. The highest concentration of glutathione is found in the liver, where it offers antioxidant support and protects tissue from reactive species produced during detoxification. This formula contains Setria® glutathione, the only brand of glutathione with research showing absorption. In a randomized clinical trial, supplementation with 250 mg of Setria® glutathione per day increased glutathione levels in the blood after one, three and six months. Setria® glutathione also showed support for antioxidant defences, indicated by decreases in the oxidized-to-reduced-glutathione ratio in whole blood after six months.
Ingredients:
Medicinal Ingredients per Capsule:
Brassica oleracea var. italica - Sulforaphane 1000 mcg 250 mg - L-Glutathione 250 mg - trans-Resveratrol 15 mg
Non-medicinal ingredients: Hydroxypropyl Methylcellulose, Water
Suggested Use
1 capsule, 1–3 times daily, with meals.
Cautions
If pregnant or lactating, consult your physician before taking this product.
It is recommended to use resveratrol cautiously in patients with hormonal disorders and those using estrogen therapy, as resveratrol may act as either an estrogen agonist or estrogen antagonist.
Consult your physician for more information.
Some studies have reported that broccoli sprout extract can affect the way that the liver breaks down medications metabolized by the cytochrome P450 system, altering the effects of these medications and possibly the dose needed for treatment.
Resveratrol and broccoli sprout extract may react with blood thinning medications.
Consult your physician for more information.